منابع مشابه
a gender-based pragmatic analysis of the use of english compliment responses by iraqi efl students:a speech act perspective
تعارفات کنش های گفتاری هستند که افراد در زندگی روزمر? خود به منظور برقراری دوستی یا تداوم روابط مسالمت آمیز به کار می برند. ساز و کار تعارف مختص زبان انگلیسی یا هر زبان دیگری نیست و پدیده ای است جهانی و در همه زبانها حضور دارد. تفاوتی که از این نظر در زبانها و فرهنگ ها وجود دارد مربوط به پاسخ به این کنش گفتاری در گفتمان است. این مطالعه به بررسی تنوع پاسخ های انگلیسی و عربی به کنش گفتاری تعارف د...
Visualizing anti-tumor immune responses in vivo.
Real-time imaging of stromal and immune cells in tumors is an emerging field that will greatly help us to understand the role of these non-malignant tumor components in tumor progression and therapy.
متن کاملTumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells
The increased presence of sialylated glycans on the tumor surface has been linked to poor prognosis, yet the effects on tumor-specific T cell immunity are hardly studied. We here show that hypersialylation of B16 melanoma substantially influences tumor growth by preventing the formation of effector T cells and facilitating the presence of high regulatory T cell (Treg) frequencies. Knock-down of...
متن کاملCarbohydrate-Mimetic Peptides for Pan Anti-Tumor Responses
Molecular mimicry is fundamental to biology and transcends to many disciplines ranging from immune pathology to drug design. Structural characterization of molecular partners has provided insight into the origins and relative importance of complementarity in mimicry. Chemical complementarity is easy to understand; amino acid sequence similarity between peptides, for example, can lead to cross-r...
متن کاملTumorigenesis and anti-tumor immune responses in Xenopus.
Despite intense study, the role of the immune system in detecting (immunosurveillance), controlling and remodeling (immunoediting) neoplasia remains elusive. We present here a comparative view of the complex interactions between neoplasia and the host immune system. We provide evidence, in the amphibian Xenopus laevis, consistent with an evolutionarily conserved and crucial role of the immune s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Immunology
سال: 2017
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.3702